Our lab is broadly interested in mechanisms which influence the biology of intestinal epithelial cells, and how these pathways are disrupted and contribute to intestinal diseases such as cancer. Colorectal cancer is one of the leading causes of cancer death in both men and women and has been rapidly shifting to affect younger people (<50 years) over the past decade. Our work aims to better understand colon cancer development and progression, as well as translate findings from the laboratory into therapies benefiting patients with intestinal diseases.